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HOMETOPICSResearch and EducationReducing the Risk of Recurrent Preterm Births Using Probiotics

Reducing the Risk of Recurrent Preterm Births Using Probiotics

Summary

Researchers have found that early pregnancy probiotics containing Clostridium butyricum may help prevent spontaneous preterm delivery

Preterm birth is a major cause of neonatal illness and death, especially among women with a history of premature delivery. Researchers in Japan explored whether taking probiotics early in pregnancy could help reduce the risk of spontaneous preterm delivery (sPTD). In a multicenter clinical trial, women who consumed probiotics containing Clostridium butyricum showed lower recurrence rates compared with national averages, suggesting that probiotic therapy may offer a simple strategy to help prevent premature births.

  • Image title： Preventing spontaneous preterm delivery using probiotics
  • Image caption： A new study suggests that probiotics supplementation during early pregnancy may help reduce the risk of recurrent spontaneous preterm delivery (sPTD). In a multicenter clinical trial, pregnant women who consumed probiotics containing Clostridium butyricum showed lower recurrence rates of sPTD compared with national averages. These findings highlight the potential of probiotic therapy as a simple strategy to support healthier pregnancy outcomes.
  • Credit： JerryLai0208 from Openverse
  • License type： CC BY-SA 2.0
  • Usage restrictions： Credit must be given to the creator. Adaptations must be shared under the same terms.

Research Details

Reducing the Risk of Recurrent Preterm Births Using Probiotics[PDF, 313KB]

Reference

Title of original paper

Prevention of Recurrent Spontaneous Preterm Delivery Using
Probiotics: Results from a Prospective, Single-Arm, Multicenter Trial

Journal

American Journal of Obstetrics and Gynecology

DOI

https://doi.org/10.1016/j.ajog.2026.02.027

Additional information for EurekAlert

Latest Article Publication Date

23 March 2026

Method of Research

Experimental study

Subject of Research

People

Conflicts of Interest Statement

The authors declare that they have no competing interests.

Media contact

Yumiko Kato

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